3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS No. | 151266-23-8 |
Remarks | Ibrutinib intermediate Futibatinib intermediate |
Product Description
- Product Name : 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- MDL No. : MFCD03787931
- Molecular Formula: C5H4IN5
- Molecular weight: 261.02
- Other Names: 7-iodo-7-deaza-8-aza-adenine; 3-iodopyrazolo[3,4-d]pyrimidin-4-amine; 3-iodo-4-aMino-1H-pyrazolo[3,4-d]pyriMidine
- Uses: An intermediate in the preparation of Ibrutinib
- 3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.